Cochlear scientist, Tissue Reprogramming

Retro develops therapies for diseases driven by the biology of aging. We focus on cellular reprogramming and autophagy to rejuvenate cell and tissue function with the ultimate aim of adding 10 years to healthy human lifespan.

Weâre building a mission-driven team of accomplished and kind individuals who embrace our startup culture of rapid iteration, transparency, and versatility.

We are seeking a highly motivated cochlear scientist to support the development of our reprogramming-based rejuvenation therapies. In this role, you will translate epigenetic reprogramming research into an anti-aging therapy by leveraging your expertise in the biology, function, and disorders of the cochlea.

This is a temporary, 3-month position with possibility to be extended or become permanent.

About you:

You are curious and open-minded - excited to learn new things and find creative, unconventional ways to approach therapeutic development. You are adaptable and have the ability to drive scientific research forward, both independently and in collaboration with cross-functional teams. You are an effective, direct communicator who thinks critically about their work and is willing to share a data-backed opposing opinion.

In this role you will:

Utilize your expertise in cochlear biology, animal models, and functional assays to investigate the rejuvenation effects and mechanisms of epigenetic reprogramming in the inner ear.

Design and execute cutting-edge experiments in gene delivery, disease modeling with animals, histology, imaging, and functional assays (both in vitro and in vivo) to generate proof-of-concept data and support the preclinical-to-clinical development pipeline.

Analyze and interpret experimental data rigorously, identifying key insights to inform decision-making and strategy.

Communicate findings and recommendations clearly through written reports, presentations, and regular updates to both internal and external collaborators, including both technical and non-technical audiences.

Lead staged gene therapy projects, working closely with fast-paced internal teams, external collaborators, and CROs to ensure that timelines, milestones, and quality standards are met.

You will thrive in this role if you:

Have at least 3 years of post-baccalaureate training experience in cochlear biology, rodent models, and functional analysis.

Possess a strong knowledge of cochlear biology, drug delivery, hearing loss models, and related functional assays.

Have hands-on experience with drug delivery into the inner ear, hearing tests using ABR/DPOAE, tissue dissection and sectioning, and IF/IHC imaging.

Are passionate about novel translational research and rejuvenation therapies.

Are intellectually curious and detail-oriented, maintaining high standards for research data while actively and accurately communicating your findings.

Itâs a bonus if you:

Have working experience of inner ear drug injection.

Have experience setting up hearing test equipment and assays, including ABR and DPOAE.

Have cellular reprogramming experiences.

Total compensation also includes generous equity and benefits including:

- Medical, dental, and vision insurance for you and your family

- Unlimited time off and 10 company holidays per year

- Daily company-sponsored lunch and snacks

Additional Information

We take pride in cultivating an environment that fosters collaboration, open communication, and authenticity. We believe that great results are best delivered by a highly creative team working in concert. We are an equal opportunity employer; we do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We are diverse in background and singular in mission.

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Cochlear scientist, Tissue Reprogramming

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